SLU-PP-332

Names

[ Name ]:
SLU-PP-332

Biological Activity

[Description]:

SLU-PP-332 is a pan-Estrogen Receptor/ERR agonist with EC50 values of 98, 230 and 430 nM for ERRα, ERRβ and ERRγ, respectively. SLUPP-332 enhances mitochondrial function and cellular respiration in skeletal muscle cell lines. SLU-PP-332 has the potential to study metabolic diseases as well as improve muscle function[1].

[Related Catalog]:

Signaling Pathways >> Others >> Estrogen Receptor/ERR

Research Areas >> Metabolic Disease

[Target]

ERRα:98 nM (EC50)

ERRβ:230 nM (EC50)

ERRγ:430 nM (EC50)

[References]

[1]. Billon C, et al. Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity. ACS Chem Biol. 2023 Apr 21;18(4):756-771.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₄N₂O₂

[ Molecular Weight ]:
290.32

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.