Atocalcitol

Names

[ Name ]:
Atocalcitol

[Synonym ]:
UNII-PR3292R3H7
Atocalcitol
Atocalcitol [INN]
Atocalcitolum
Atocalcitolum [INN-Latin]
(1S,3R,5Z,7E,20R)-20-(3-(2-Hydroxypropan-2-yl)benzyloxymethyl)-9,10-secopregna-5,7,10(19)-triene-1alpha,3beta-diol

Biological Activity

[Description]:

Atocalcitol, a vitamin D3 analogue, is used in the study for psoriasis[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Xuan Xu, et al. The Immunogenetics of Psoriasis and Implications for Drug Repositioning. Int J Mol Sci. 2017 Dec 8;18(12):2650.

[2]. Nicklas H Staunstrup, et al. A Sleeping Beauty DNA transposon-based genetic sensor for functional screening of vitamin D3 analogues. BMC Biotechnol. 2011 Apr 7;11:33.

Chemical & Physical Properties

[ Density]:
1.12g/cm3

[ Boiling Point ]:
636.3ºC at 760mmHg

[ Molecular Formula ]:
C₃₂H₄₆O₄

[ Molecular Weight ]:
494.70500

[ Flash Point ]:
338.6ºC

[ Exact Mass ]:
494.34000

[ PSA ]:
69.92000

[ LogP ]:
6.20770

[ Index of Refraction ]:
1.579