Benactyzine
Names
[ CAS No. ]:
302-40-9
[ Name ]:
Benactyzine
[Synonym ]:
Benzilsaeure-(2-diaethylamino-aethylester)
Benzilic acid,2-(diethylamino)ethyl ester
Benzactyzine
Benactyzinum [INN-Latin]
Benactizina [Italian]
Diphenyl-glykolsaeure-<2-diaethylamino-aethylester>
Benactyzin
Benacticina [INN-Spanish]
2-diethylaminoethyl benzilate
Diethylaminoethyl benzilate
BENACTYZINE
Benactizina [DCIT]
Chemical & Physical Properties
[ Density]:
1.115 g/cm3
[ Boiling Point ]:
409.3ºC at 760 mmHg
[ Melting Point ]:
51ºC
[ Molecular Formula ]:
C20H25NO3
[ Molecular Weight ]:
327.41700
[ Flash Point ]:
201.4ºC
[ Exact Mass ]:
327.18300
[ PSA ]:
49.77000
[ LogP ]:
2.80750
[ Index of Refraction ]:
1.557
[ Storage condition ]:
2-8°C
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DD2480000
- CHEMICAL NAME :
- Benzilic acid, 2-(diethylamino)ethyl ester
- CAS REGISTRY NUMBER :
- 302-40-9
- BEILSTEIN REFERENCE NO. :
- 2156821
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C20-H25-N-O3
- MOLECULAR WEIGHT :
- 327.46
- WISWESSER LINE NOTATION :
- QXR&R&VO2N2&2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 100 ug/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 135 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 159 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
MUTATION DATA
- TEST SYSTEM :
- Rodent - hamster
- DOSE/DURATION :
- 10 mg/kg
- REFERENCE :
- ACNSAX Activitas Nervosa Superior. (Avicenum, Malostranske nam. 28, Prague 1, Czechoslovakia) V.1- 1959- Volume(issue)/page/year: 17,253,1975
Safety Information
[ Hazard Codes ]:
T
[ Risk Phrases ]:
23/24/25
[ Safety Phrases ]:
36/37/39-45
[ HS Code ]:
2922509090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922509090
[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%