Pin1 modulator 1

Names

[ Name ]:
Pin1 modulator 1

[Synonym ]:
4-[(5Z)-5-(1-Naphthylmethylene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoic acid
3-Thiazolidinebutanoic acid, 5-(1-naphthalenylmethylene)-4-oxo-2-thioxo-, (5Z)-

Biological Activity

[Description]:

Pin1 modulator 1 (compound IIb-219) is a modulator that specifically targets β-Catenin and inhibits the Wnt pathway. Pin1 modulator 1 can be used in the study of Wnt-mediated related diseases, such as cancer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Stem Cell/Wnt >> Wnt

[References]

[1]. Ramanuj Dasgupta, et al. Oxazole and thiazole compounds as b-catenin modulators and uses thereof. Patent WO2009097113A2.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
592.2±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₁₅NO₃S₂

[ Molecular Weight ]:
357.45

[ Flash Point ]:
312.0±32.9 °C

[ Exact Mass ]:
357.049347

[ LogP ]:
3.12

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.745

Related Compounds

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