3-Indoleacrylic acid

Names

[ Name ]:
3-Indoleacrylic acid

[Synonym ]:
3-Indoleacrylic acid
(E)-3-(indol-3-yl)acrylic acid
2-Propenoic acid, 3-(1H-indol-3-yl)-, (2E)-
INDOLE ACRYLIC ACID
INDOLE-3-ACRYLIC ACID
2-Propenoic acid, 3- (1H-indol-3-yl)-
Indole-3-butyic acid
3-(3-INDOLYL)ACRYLIC ACID
(2E)-3-(1H-Indol-3-yl)acrylic acid
trans-Indole-3-acrylic acid
(2E)-3-(1H-indol-3-yl)prop-2-enoic acid
Indole-3-crylic acid
Trans-3-Indoleacrylicn
EINECS 214-872-7
MFCD00005633
RARECHEM BK HD 0025

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
432.8±20.0 °C at 760 mmHg

[ Melting Point ]:
185 °C (dec.)(lit.)

[ Molecular Formula ]:
C₁₁H₉NO₂

[ Molecular Weight ]:
187.195

[ Flash Point ]:
215.6±21.8 °C

[ Exact Mass ]:
187.063324

[ PSA ]:
53.09000

[ LogP ]:
2.34

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.750

[ Water Solubility ]:
freely soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
NL3680000

Articles

Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.

J. Med. Chem. 54 , 5320, (2011)

Tryptophan catabolism mediated by indoleamine 2,3-dioxygenase (IDO) is an important mechanism of peripheral immune tolerance contributing to tumoral immune resistance. IDO inhibition is thus an active...

Structural insight into the inhibition of human kynurenine aminotransferase I/glutamine transaminase K.

J. Med. Chem. 52 , 2786-93, (2009)

Human kynurenine aminotransferase I (hKAT I) catalyzes the formation of kynurenic acid, a neuroactive compound. Here, we report three high-resolution crystal structures (1.50-1.55 A) of hKAT I that ar...

Glycodendrimers and Modified ELISAs: Tools to Elucidate Multivalent Interactions of Galectins 1 and 3.

Molecules 20 , 7059-96, (2015)

Multivalent protein-carbohydrate interactions that are mediated by sugar-binding proteins, i.e., lectins, have been implicated in a myriad of intercellular recognition processes associated with tumor ...