DL-3-Phenylalanine-d8

Names

[ CAS No. ]:
29909-00-0

[ Name ]:
DL-3-Phenylalanine-d8

[Synonym ]:
E-3-phenylpropenoic acid
2-amino-2,3,3-trideuterio-3-pentadeuteriophenyl-propionic acid
Phenylacetylmethylen-triphenylphosphoran
phenylacetylmethylenetriphenylphosphorane
Phenylacrylic acid
2-Oxo-3-phenylpropylidenetriphenylphosphorane
3-phenyl-2E-propenoic acid
MFCD00190498
Phenylalanin-d8

Biological Activity

[Description]:

DL-3-Phenylalanine-d8 is the deuterium labeled DL-3-Phenylalanine[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.26 g/cm3

[ Boiling Point ]:
307.5ºC at 760 mmHg

[ Melting Point ]:
266-267ºC (dec.)(lit.)

[ Molecular Formula ]:
C9H3D8NO2

[ Molecular Weight ]:
173.24

[ Flash Point ]:
139.8ºC

[ Exact Mass ]:
173.12900

[ PSA ]:
63.32000

[ LogP ]:
1.34130

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Related Compounds