Silidianin
Names
[ CAS No. ]:
29782-68-1
[ Name ]:
Silidianin
[Synonym ]:
Silidianin
Silydianin
(1R,3R,6R,7R,10R)-3-Hydroxy-10-(4-hydroxy-3-methoxyphenyl)-8-[(2R,3R)-3,5,7-trihydroxy-4-oxo-3,4-dihydro-2H-chromen-2-yl]-4-oxatricyclo[4.3.1.0]dec-8-en-2-one
Silydianin (20 mg)
Silychristin
3,6-Methanobenzofuran-7(6H)-one, 4-[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-4-oxo-2H-1-benzopyran-2-yl]-2,3,3a,7a-tetrahydro-7a-hydroxy-8-(4-hydroxy-3-methoxyphenyl)-, (3R,3aR,6R,7aR,8R)-
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
819.0±65.0 °C at 760 mmHg
[ Melting Point ]:
191 °C
[ Molecular Formula ]:
C25H22O10
[ Molecular Weight ]:
482.436
[ Flash Point ]:
285.0±27.8 °C
[ Exact Mass ]:
482.121307
[ PSA ]:
162.98000
[ LogP ]:
1.84
[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C
[ Index of Refraction ]:
1.747
[ Storage condition ]:
2-8°C
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Precautionary Statements ]:
P301 + P312 + P330
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
22
[ Safety Phrases ]:
22-45
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3.0
Articles
Pharmacol. Res. 25(2) , 147-54, (1992)
The effect of several flavanolignans (silicristin, silidianin, silybin and isosilybin) present in silymarin, the extract of Silybum marianum fruits, was tested on lipid peroxidation in rat liver micro...
[Silymarin in the treatment of chronic liver diseases: past and future].Orv. Hetil. 149(51) , 2413-8, (2008)
In the treatment of chronic liver diseases adequate therapy can be chosen only in the knowledge of pathogenetic processes. In the liver diseases caused by oxidative stress (alcoholic and non-alcoholic...
Separation and characterization of silybin, isosilybin, silydianin and silychristin in milk thistle extract by liquid chromatography-electrospray tandem mass spectrometry.J. Chromatogr. A. 1116(1-2) , 57-68, (2006)
A selective and sensitive liquid chromatography/tandem mass spectrometry (LC/MS/MS) method has been developed for the characterization of silymarin in commercially available milk thistle extract. In t...