METTL3-IN-5

Names

[ Name ]:
METTL3-IN-5

Biological Activity

[Description]:

METTL3-IN-5 (Compound 13) is a METTL3 inhibitor. METTL3-IN-5 inhibits MOLM-13 growth with an IC50 less than 2 μM. METTL3-IN-5 has weak hERG inhibitory activity (IC50 >30 μM). METTL3-IN-5 can be used for AML research[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

METTL3[1]

[References]

[1]. Zhong Chen, et al. Mettl3 inhibitor and composition, and application of same in medicine. WO2023151697 A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₂FN₅O₂S

[ Molecular Weight ]:
451.52

Related Compounds

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