Friedelin 3,4-lactone

Names

[ Name ]:
Friedelin 3,4-lactone

[Synonym ]:
Friedelalacton
3,4-seco-friedelan-4,3-olide
4-Oxa-A-homo-friedelan-3-on
4-oxa-A-homo-friedelan-3-one
Friedelolactone
3a-oxa-3a-homofriedelan-3-one

Biological Activity

[Description]:

Friedelin-3,4-lactone (Compound 4) is a triterpene can be isolated from the leaves of Garcia parViflora with weak antitumor activity[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

Friedelin-3,4-lactone (Compound 4) 对 U251 细胞具有细胞毒性，IC50 为 17.1 μM[1]。

[References]

[1]. Reyes BM, et al. Triterpenes from Garcia parviflora. Cytotoxic evaluation of natural and semisynthetic friedelanes. J Nat Prod. 2010 Nov 29;73(11):1839-45.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₀H₅₀O₂

[ Molecular Weight ]:
442.72

[ Exact Mass ]:
442.38100

[ PSA ]:
26.30000

[ LogP ]:
8.18350

Friedelin 3,4-lactone

Names

Biological Activity

Chemical & Physical Properties

Related Compounds