(+)-BETA-HYDRASTINE

[ Density]:
1.339g/cm3

[ Boiling Point ]:
548.8ºC at 760mmHg

[ Molecular Formula ]:
C₂₁H₂₁NO₆

[ Molecular Weight ]:
383.39500

[ Flash Point ]:
285.7ºC

[ Exact Mass ]:
383.13700

[ PSA ]:
66.46000

[ LogP ]:
2.81110

[ Vapour Pressure ]:
4.28E-12mmHg at 25°C

[ Index of Refraction ]:
1.614

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Expanding the repertoire of small molecule transcriptional activation domains.

Bioorg. Med. Chem. 17 , 1034-43, (2009)

Molecules that can reconstitute the function of transcriptional activators hold enormous potential as therapeutic agents and as mechanistic probes. Previously we described an isoxazolidine bearing fun...

Differential modulation of respiratory neuronal discharge patterns by GABA(A) receptor and apamin-sensitive K(+) channel antagonism.

J. Neurophysiol. 86(5) , 2363-73, (2001)

The discharge patterns of respiratory neurons of the caudal ventral respiratory group (cVRG) appear to be subject to potent GABAergic gain modulation. Local application of the GABA(A) receptor antagon...

Effects of (1R,9S)-beta-hydrastine on l-DOPA-induced cytotoxicity in PC12 cells.

Eur. J. Pharmacol. 488(1-3) , 71-7, (2004)

(1R,9S)-beta-Hydrastine in lower concentrations of 10-50 microM inhibits dopamine biosynthesis in PC12 cells. In this study, the effects of (1R,9S)-beta-hydrastine on L-DOPA (L-3,4-dihydroxyphenylalan...

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