4-CPPC

Names

[ Name ]:
4-CPPC

[Synonym ]:
4-(3-Carboxyphenyl)-2,5-pyridinedicarboxylic acid
2,5-Pyridinedicarboxylic acid, 4-(3-carboxyphenyl)-

Biological Activity

[Description]:

4-CPPC is the first reversible and selective inhibitor of pro-inflammatory protein macrophage migration inhibitory factor-2 (MIF-2) with Ki of 33 uM, 13-fold selectivity for human MIF-2 versus human MIF-1.

[References]

References 1. Pantouris G, et al. Biochemistry. 2018 Jun 12. doi: 10.1021/acs.biochem.8b00344. View Related Products by Target Other Targets

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
595.2±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₄H₉NO₆

[ Molecular Weight ]:
287.224

[ Flash Point ]:
313.8±30.1 °C

[ Exact Mass ]:
287.042999

[ LogP ]:
1.01

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.675

Related Compounds

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