HIV-1 inhibitor-56

Names

[ CAS No. ]:
2952530-45-7

[ Name ]:
HIV-1 inhibitor-56

Biological Activity

[Description]:

HIV-1 inhibitor-56 (compound 12126065) is a potent HIV-1 non-nucleoside reverse transcriptase inhibitor. HIV-1 inhibitor-56 has antiviral activity against wild-type HIV-1 in TZM cells with an EC50 value of 0.24 nM. HIV-1 inhibitor-56 penetrates the blood-brain barrier[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV
Research Areas >> Infection

[References]

[1]. Lane T, et, al. N-Phenyl-1-(phenylsulfonyl)-1H-1,2,4-triazol-3-amine as a New Class of HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor. J Med Chem. 2023 May 11;66(9):6193-6217.  

Chemical & Physical Properties

[ Molecular Formula ]:
C22H14ClN7O2S

[ Molecular Weight ]:
475.91

Related Compounds

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