Pseudolycorine

Names

[ Name ]:
Pseudolycorine

[Synonym ]:
(1S,2S,11bS,11cS)-9-Methoxy-1,2,4,5,11b,11c-hexahydro-7H-pyrrolo[3,2,1-de]phenanthridine-1,2,10-triol
(-)-pseudolycorine
9-Methoxy-galanth-3-en-1α,2β,10-triol
Pseudolycorin
9-methoxy-galanth-3-ene-1α,2β,10-triol

Biological Activity

[Description]:

Pseudolycorine is an Amaryllidaceae alkaloid with anticancer activity[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

Pseudolycorine 显示出生长抑制活性，对 A549、OE21、Hs683、U373 和 B16F10 细胞的 IC50 值分别为 7.4 μM、7.9 μM、7.9 μM、7.8 μM 和 7.5 μM[1]。

[References]

[1]. Gwendoline Van Goietsenoven, et al. Amaryllidaceae alkaloids belonging to different structural subgroups display activity against apoptosis-resistant cancer cells. J Nat Prod. 2010 Jul 23;73(7):1223-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₉NO₄

[ Molecular Weight ]:
289.32600

[ Exact Mass ]:
289.13100

[ PSA ]:
73.16000

[ LogP ]:
0.67200

Related Compounds

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