Pim-1 kinase inhibitor 6

Names

[ CAS No. ]:
2928606-69-1

[ Name ]:
Pim-1 kinase inhibitor 6

Biological Activity

[Description]:

Pim-1 kinase inhibitor 6 (Compound 4d) is a potent Pim-1 kinase inhibitor with IC50 value of 0.46 μM, and has significant cytotoxic effect on cancer cells[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> JAK/STAT Signaling >> Pim

[References]

[1]. Basem Mansour, et al. Cyanopyridinone- and Cyanopyridine-Based Cancer Cell Pim-1 Inhibitors: Design, Synthesis, Radiolabeling, Biodistribution, and Molecular Modeling Simulation. ACS Omega. 2023 May 24;8(22):19351-19366.  

Chemical & Physical Properties

[ Molecular Formula ]:
C21H10BrCl2N3

[ Molecular Weight ]:
455.13

Related Compounds