MDM2/XIAP-IN-3

Names

[ CAS No. ]:
2925583-17-9

[ Name ]:
MDM2/XIAP-IN-3

Biological Activity

[Description]:

MDM2/XIAP-IN-3 (compound 3e) is a dual MDM2/XIAP inhibitor. MDM2/XIAP-IN-3 reduces MDM2 and XIAP protein levels and increases p53 expression, thereby inhibiting cancer cell growth and causing cell death[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Apoptosis >> MDM-2/p53
Signaling Pathways >> Apoptosis >> IAP

[References]

[1]. Albadari N, et al. Synthesis and biological evaluation of dual MDM2/XIAP inhibitors based on the tetrahydroquinoline scaffold. Eur J Med Chem. 2023 Jul 5;255:115423.  

Chemical & Physical Properties

[ Molecular Formula ]:
C29H30N2O5S

[ Molecular Weight ]:
518.62

Related Compounds

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