HIV-1 protease-IN-12

Names

[ CAS No. ]:
2925287-59-6

[ Name ]:
HIV-1 protease-IN-12

Biological Activity

[Description]:

HIV-1 protease-IN-12 (compound 35b) is a HIV-1 protease inhibitor with an IC50 of 0.51 nM. HIV-1 protease-IN-12 also inhibits drug-resistant variant[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Protease

[References]

[1]. Huiyu Zhou, et al. Design, synthesis, and biological evaluation of novel HIV-1 protease inhibitors containing pyrrolidine-derived P2 ligands to combat drug-resistant variant. Eur J Med Chem. 2023 Jul 5;255:115389.  

Chemical & Physical Properties

[ Molecular Formula ]:
C25H35N3O5S

[ Molecular Weight ]:
489.63

Related Compounds

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