Chitin synthase inhibitor 13

Names

[ CAS No. ]:
2925228-79-9

[ Name ]:
Chitin synthase inhibitor 13

Biological Activity

[Description]:

Chitin synthase inhibitor 13 (compound 12g) is a non-competitive inhibitor of chitin synthase, with an IC50 of 106.7 μM. Chitin synthase inhibitor 13 exhibits a broad-spectrum of antifungal activity[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Du C, et, al. Design, synthesis and biological evaluation of novel spiro-quinazolinone derivatives as chitin synthase inhibitors and antifungal agents. Eur J Med Chem. 2023 Jul 5;255:115388.  

Chemical & Physical Properties

[ Molecular Formula ]:
C21H19N5O5S

[ Molecular Weight ]:
453.47

Related Compounds

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