WU-04

Names

[ CAS No. ]:
2921711-74-0

[ Name ]:
WU-04

Biological Activity

[Description]:

WU-04 is a non-covalent inhibitor of SARS-CoV-2, targeting the 3CLpro protein. WU-04 has high inhibitory effect on the 3CLpro protein of 6 SARS-CoV-2 variants (Alpha, Beta, Gamma, Delta, Lambda and Omicron) and 2 coronaviruses (SARS-CoV and MERS-CoV)[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> SARS-CoV

[References]

[1]. Wu J, et al. The molecular mechanism of non-covalent inhibitor WU-04 targeting SARS-CoV-2 3CLpro and computational evaluation of its effectiveness against mainstream coronaviruses. Phys Chem Chem Phys. 2023 Sep 13;25(35):23555-23567.. .  

Chemical & Physical Properties

[ Molecular Formula ]:
C24H24BrN5O4

[ Molecular Weight ]:
526.38

Related Compounds

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