Galectin-3 antagonist 1

Names

[ Name ]:
Galectin-3 antagonist 1

Biological Activity

[Description]:

Galectin-3 antagonist 1 (compound 15) is a potent and selective Galectin-3 (Gal-3) antagonist with Kd value of 5.3 μM. Meanwhile, Galectin-3 antagonist 1 binds to various Galectin with Kd values of 250 μM (Gal-4N), 18 μM (Gal-4C), 450 μM (Gal-8C), respectively[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Kd: 5.3 μM (Gal-3), 250 μM (Gal-4N), 18 μM (Gal-4C), 450 μM (Gal-8C)[1]

[References]

[1]. Bum-Erdene K, et al. Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia. J Med Chem. 2022 Apr 28;65(8):5975-5989.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₂ClNO₁₀

[ Molecular Weight ]:
495.86

Related Compounds

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