Daidzein-d6

Names

[ CAS No. ]:
291759-05-2

[ Name ]:
Daidzein-d6

[Synonym ]:
Daidzein-d6
Daidzein-2 inverted exclamation mark,3 inverted exclamation mark,5 inverted exclamation mark,6,6 inverted exclamation mark,8-d6
4',7-Dihydroxyisoflavone-d6

Biological Activity

[Description]:

Daidzein-d6 is a deuterium labeled Daidzein (HY-N0019). Daidzein is a soy isoflavone, which acts as a PPAR activator.

[Related Catalog]:

Research Areas >> Endocrinology

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246.  

[2]. Kim E, et al. Daidzein Augments Cholesterol Homeostasis via ApoE to Promote Functional Recovery in Chronic Stroke. J Neurosci. 2015 Nov 11;35(45):15113-26.  

[3]. Sakamoto Y1, et al. The Dietary Isoflavone Daidzein Reduces Expression of Pro-Inflammatory Genes through PPARα/γ and JNK Pathways in Adipocyte and Macrophage Co-Cultures. PLoS One. 2016 Feb 22;11(2):e0149676.  

Chemical & Physical Properties

[ Density]:
1.478g/cm3

[ Boiling Point ]:
512.837ºC at 760 mmHg

[ Melting Point ]:
315-323ºC (dec)

[ Molecular Formula ]:
C15H4D6O4

[ Molecular Weight ]:
260.27

[ Flash Point ]:
201.215ºC

[ Exact Mass ]:
260.09600

[ PSA ]:
70.67000

[ LogP ]:
2.87120

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.699

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream