Cisd2 agonist 1

Names

[ CAS No. ]:
2916371-54-3

[ Name ]:
Cisd2 agonist 1

Biological Activity

[Description]:

Cisd2 agonist 1 (Compound 4q) is a Cisd2 agonist (EC50: 34 nM). Cisd2 agonist 1 enhances the Cisd2 expression and improves the pathological changes in the fatty livers. Cisd2 agonist 1 has good metabolic stability. Cisd2 agonist 1 can be used for research of NAFLD[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Yao CH, et al. Discovery of tetrasubstituted thiophenes as Cisd2 activators: A potential novel therapeutic option in nonalcoholic fatty liver disease. Eur J Med Chem. 2023 Oct 5;258:115583.  

Chemical & Physical Properties

[ Molecular Formula ]:
C14H13FN2O3S

[ Molecular Weight ]:
308.33

Related Compounds

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