PROTAC IRAK4 degrader-8

Names

[ CAS No. ]:
2911615-06-8

[ Name ]:
PROTAC IRAK4 degrader-8

Biological Activity

[Description]:

PROTAC IRAK4 degrader-8 (compound 2) is a PROTAC targeting to IRAK4 (IC50=15.5 nM)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Immunology/Inflammation >> IRAK

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> IRAK

[Target]

IRAK4

[References]

[1]. Ye Z, et al. Preparation of (pyrazolyl)pyrazolo[1,5-a]pyrimidinyl carboxamide derivatives as IRAK4 degrading agents and its applications. China, CN115710274 A. 2023-02-24.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₃H₅₀ClF₂N₁₁O₅

[ Molecular Weight ]:
874.38

Related Compounds

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