4-ethylresorcinol

Names

[ Name ]:
4-ethylresorcinol

[Synonym ]:
1,3-Benzenediol,4-ethyl
1,3-Dihydroxy-4-ethylbenzene
1,3-Benzenediol, 4-ethyl-
4-ethylresorcinol
EINECS 220-777-1
2,4-Dihydroxyethylbenzene
4-Ethylbenzol-1,3-diol
MFCD00002283
6-Ethylresorcinol
2,4-Dihydroxy-1-ethylbenzene
4-Ethyl-1,3-benzenediol
4-Ethyl-resorcinol
4-ethylbenzene-1,3-diol
Resorcinol,4-ethyl

Biological Activity

[Description]:

4-Ethylresorcinol, a derivative of resorcinol, can act as substrates of tyrosinase. 4-Ethylresorcinol possess hypopigmentary effects. 4-Ethylresorcinol attenuates mRNA and protein expression of tyrosinase-related protein (TRP)-2, and possessed antioxidative effect by inhibiting lipid peroxidation[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Jimenez AG, et, al. Characterization of the action of tyrosinase on resorcinols. Bioorg Med Chem. 2016 Sep 15;24(18):4434-4443.

[2]. Lam RYY, et, al. Mechanistic studies of anti-hyperpigmentary compounds: elucidating their inhibitory and regulatory actions. Int J Mol Sci. 2014 Aug 21;15(8):14649-68.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
273.8±10.0 °C at 760 mmHg

[ Melting Point ]:
95-98 °C(lit.)

[ Molecular Formula ]:
C₈H₁₀O₂

[ Molecular Weight ]:
138.164

[ Flash Point ]:
134.4±13.6 °C

[ Exact Mass ]:
138.068085

[ PSA ]:
40.46000

[ LogP ]:
1.75

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.579

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2907299090

[ Summary ]:
2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

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