BDM91514

Names

[ CAS No. ]:
2892824-90-5

[ Name ]:
BDM91514

Biological Activity

[Description]:

BDM91514 improves antibiotic potency through AcrB inhibition. BDM91514 prevents the growth of E. coliBW25113 (EC90: 8 μM) in the presence of 8 μg/mL Pyridomycin. BDM91514 has suitable plasma and microsomal stability[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Compagne N, et al. Optimization of pyridylpiperazine-based inhibitors of the Escherichia coli AcrAB-TolC efflux pump. Eur J Med Chem. 2023 Jul 7;259:115630.  

Chemical & Physical Properties

[ Molecular Formula ]:
C13H19Cl3N6O

[ Molecular Weight ]:
381.69

Related Compounds

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