Phosphatase-IN-1

Names

[ Name ]:
Phosphatase-IN-1

Biological Activity

[Description]:

Phosphatase-IN-1 (compound II-8), a propranolol (HY-B0573B) derivative, is a phosphatidate phosphatase (Pah) inhibitor. Phosphatase-IN-1 can binds to MoPah1, with an affinity constant of 19.8 μM. Phosphatase-IN-1 inhibits growth of plant pathogens and shows anti-fungal ability. Phosphatase-IN-1 is not toxic to rice seedlings and wheat heads[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Zhao J, et al. Identification of propranolol and derivatives that are chemical inhibitors of phosphatidate phosphatase as potential broad-spectrum fungicides. Plant Commun. 2023 Aug 30:100679.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₆Cl₂FNO₂

[ Molecular Weight ]:
344.21

Related Compounds

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