Anticancer agent 131

Names

[ CAS No. ]:
2864443-47-8

[ Name ]:
Anticancer agent 131

Biological Activity

[Description]:

HCT-116-IN-1, a γ-lactam-fused pyridone derivative, has anticancer activity and displayed high cytotoxicity against HCT116 cells with an IC50 of 5.59 μM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. An YN, et.al. Unexpected Cascade Sequence Forming the C(sp3)-N/C(sp2)-C(sp2) Bond: Direct Access to γ-Lactam-Fused Pyridones with Anticancer Activity. J Org Chem. 2023 Jul 7;88(13):7998-8009.  

Chemical & Physical Properties

[ Molecular Formula ]:
C33H24ClN3O5

[ Molecular Weight ]:
578.01

Related Compounds

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