Thalidomide-5-NH-PEG1-NH2 hydrochloride

Names

[ CAS No. ]:
2863634-98-2

[ Name ]:
Thalidomide-5-NH-PEG1-NH2 hydrochloride

Biological Activity

[Description]:

Thalidomide-5-NH-PEG1-NH2 hydrochloride is a Thalidomide (HY-14658)-based cereblon ligand that recruits CRBN proteins. Thalidomide-5-NH-PEG1-NH2 hydrochloride can be connected to the target protein ligand through a linker to form a PROTAC molecule. For example, THAL-SNS-032 (HY-123937).

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> Ligand for E3 Ligase

Chemical & Physical Properties

[ Molecular Formula ]:
C17H21ClN4O5

[ Molecular Weight ]:
396.83

Related Compounds

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