Theaflavin-3'-gallate

Names

[ Name ]:
Theaflavin-3'-gallate

[Synonym ]:
theaflavin-3-gallate
Theaflavine 3-O-gallate
THEAFLAVINMONOGALLATEB
Benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-2-[(6R)-4-[(2R,3R)-3,4-dihydro-3,5,7-trihydroxy-2H-1-benzopyran-2-yl]-6,7,8,9-tetrahydro-1,2-dihydroxy-9-oxo-5H-benzocyclohepten-6-yl]-3,4-dihydro-5,7-dihydroxy-2H-1-benzopyran-3-yl ester
(2R,3R)-2-{(6R)-1,2-Dihydroxy-9-oxo-4-[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]-6,7,8,9-tetrahydro-5H-benzo[7]annulen-6-yl}-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate
Theaflavin 2B
theaflavin-3-O-gallate
Theaflavin 3'-gallate

Biological Activity

[Description]:

Theaflavin-3'-gallate, a black tea theaflavin monomer, is regarded as the biologically important active component of black tea and provides health benefits. Theaflavin-3'-gallate acts as prooxidants and induces oxidative stress in the carcinoma cells. Theaflavin-3'-gallate reacts directly with reduced glutathione (GSH) in a time- and concentration-dependent manner[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Babich H, et al. Theaflavin-3-gallate and theaflavin-3'-gallate, polyphenols in black tea with prooxidant properties. Basic Clin Pharmacol Toxicol. 2008 Jul;103(1):66-74.

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
1135.6±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₆H₃₂O₁₅

[ Molecular Weight ]:
704.630

[ Flash Point ]:
361.0±27.8 °C

[ Exact Mass ]:
704.174133

[ PSA ]:
264.13000

[ LogP ]:
4.61

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.836

[ Storage condition ]:
2-8℃

Safety Information

[ HS Code ]:
29182900

Theaflavin-3'-gallate

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds