TH-Z816

Names

[ Name ]:
TH-Z816

Biological Activity

[Description]:

TH-Z816 is a reversible inhibitor againstKRAS(G12D)mutation with an IC50 value of 14 μM, which can be used in cancer research[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> GPCR/G Protein >> Ras

[References]

[1]. Zhongwei Mao, et al. KRAS(G12D) can be targeted by potent inhibitors via formation of salt bridge. Cell Discov. 2022 Jan 25;8(1):5.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₃₈N₆O

[ Molecular Weight ]:
486.65

Related Compounds

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