NMB-1

Names

[ CAS No. ]:
2843557-76-4

[ Name ]:
NMB-1

Biological Activity

[Description]:

NMB-1 is a conopeptide analogue. NMB-1 selectively inhibits sustained mechanically activated currents in sensory neurons (IC50: 1 μM). NMB-1 inhibits mechanical pain. NMB-1 can be used for research of hearing and pressure-evoked pain[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Drew LJ, et al. High-threshold mechanosensitive ion channels blocked by a novel conopeptide mediate pressure-evoked pain. PLoS One. 2007 Jun 13;2(6):e515.  

[2]. Raouf R, et al. Inhibition of somatosensory mechanotransduction by annexin A6. Sci Signal. 2018 Jun 19;11(535):eaao2060.  

Chemical & Physical Properties

[ Molecular Formula ]:
C111H164N36O21S4

[ Molecular Weight ]:
2466.98

Related Compounds

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