Cetilistat

Names

[ Name ]:
Cetilistat

[Synonym ]:
2-Hexadecyloxy-6-methyl-4H-3,1-benzoxazin-4-one
2-(Hexadecycloxy)-6-methyl-4H-3,1-benzoxazin-4-one
4H-3,1-Benzoxazin-4-one, 2-(hexadecyloxy)-6-methyl-
2-(Hexadecyloxy)-6-methyl-4H-3,1-benzoxazin-4-one
Cetilstat

Biological Activity

[Description]:

Cetilistat is an inhibitor of pancreatic and gastrointestinal lipases. It has great treatment of obesity in both diabetic and non-diabetic patients.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Andrew Bryson, Stephan de la Motte,et al. Reduction of dietary fat absorption by the novel gastrointestinal lipase inhibitor cetilistat in healthy volunteers.Br J Clin Pharmacol. 2009 Mar; 67(3): 309–315.

[2]. Melvin George, Muthukumar Rajaram,et al. New and Emerging Drug Molecules Against Obesity.J CARDIOVASC PHARMACOL THER January 2014 vol. 19 no. 1 65-76

[3]. Rebeca Carter, Angelina Mouralidarane,et al. Recent advancements in drug treatment of obesity.Clin Med October 1, 2012 vol. 12 no. 5 456-460

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
509.7±43.0 °C at 760 mmHg

[ Melting Point ]:
74°C

[ Molecular Formula ]:
C₂₅H₃₉NO₃

[ Molecular Weight ]:
401.582

[ Flash Point ]:
158.9±22.6 °C

[ Exact Mass ]:
401.292999

[ PSA ]:
52.33000

[ LogP ]:
9.93

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.521

MSDS

Click to get detail MSDS

Safety Information

[ HS Code ]:
2942000000

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2942000000

Related Compounds

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