Cbl-b-IN-11

Names

[ Name ]:
Cbl-b-IN-11

Biological Activity

[Description]:

Cbl-b-IN-11 (Compound 466) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 6.4 nM and 6.1 nM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> E1/E2/E3 Enzyme

[Target]

IC50: 6.1 nM (c-Cbl), 6.4 nM (Cbl-b)[1]

[References]

[1]. Jun Liang, et al. Lactams as cbl-b inhibitors. Patent WO2022169997A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₃₅F₅N₆O

[ Molecular Weight ]:
602.64

Related Compounds

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