HCoV-OC43-IN-1

Names

[ Name ]:
HCoV-OC43-IN-1

Biological Activity

[Description]:

HCoV-OC43-IN-1 (Compound IV-16) is a coronavirus HCoV-OC43 inhibitor. HCoV-OC43-IN-1 has antiviral efficacy (EC50: 90 nM). HCoV-OC43-IN-1 inhibits the mRNA level and expression of viral nucleocapsid protein (NP)[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> SARS-CoV

[References]

[1]. Zhou S, et al. Design, synthesis, and structure-activity relationships of a novel class of quinazoline derivatives as coronavirus inhibitors. Eur J Med Chem. 2023 Sep 25;261:115831.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₂F₆N₄O₂

[ Molecular Weight ]:
500.44

Related Compounds

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