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2,8-Diazaspiro[4.5]decane-1,3-dione,8-[4-(4-fluorophenyl)-4-oxobutyl]-2-methyl-

Names

[ CAS No. ]:
2804-00-4

[ Name ]:
2,8-Diazaspiro[4.5]decane-1,3-dione,8-[4-(4-fluorophenyl)-4-oxobutyl]-2-methyl-

[Synonym ]:
F-33
Roxoperonum [INN-Latin]
Roxoperon [INN-Spanish]
8-[4-(4-fluoro-phenyl)-4-oxo-butyl]-2-methyl-2,8-diaza-spiro[4.5]decane-1,3-dione
FR-33
8-(3-(p-Fluorobenzoyl)propyl)-2-methyl-2,8-diazaspiro(4.5)decane-1,3-dione
Roxoperone
R 7158

Chemical & Physical Properties

[ Density]:
1.26g/cm3

[ Boiling Point ]:
530.9ºC at 760mmHg

[ Molecular Formula ]:
C19H23FN2O3

[ Molecular Weight ]:
346.39600

[ Flash Point ]:
274.9ºC

[ Exact Mass ]:
346.16900

[ PSA ]:
57.69000

[ LogP ]:
2.13530

[ Vapour Pressure ]:
2.36E-11mmHg at 25°C

[ Index of Refraction ]:
1.579

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HM2650000
CHEMICAL NAME :
2,8-Diazaspiro(4,5)decane-1,3-dione, 8-(3-(p-fluorobenzoyl)propyl)-2-methyl-
CAS REGISTRY NUMBER :
2804-00-4
BEILSTEIN REFERENCE NO. :
0763388
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C19-H23-F-N2-O3
MOLECULAR WEIGHT :
346.44
WISWESSER LINE NOTATION :
T6N DXTJ A3VR DF& D-& CT5VNVX EHJ A

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
92 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,189,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
193 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,189,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
90 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,189,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,189,1972

Safety Information

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

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