14-deoxycaesalpin

Names

[ Name ]:
14-deoxycaesalpin

[Synonym ]:
Phenanthro[3,2-b]furan-1,2,4a(2H)-triol, 1,3,4,5,6,6a,7,11,11a,11b-decahydro-4,4,7,11b-tetramethyl-, 1,2-diacetate, (1R,2S,4aR,6aS,7R,11aS,11bS)-
(1R,2S,4aR,6aS,7R,11aS,11bS)-4a-Hydroxy-4,4,7,11b-tetramethyl-1,2,3,4,4a,5,6,6a,7,11,11a,11b-dodecahydrophenanthro[3,2-b]furan-1,2-diyl diacetate

Biological Activity

[Description]:

(+)-14-Deoxy-ε-caesalpin (14-Deoxy-ε-caesalpin), a cassane diterpenoid, inhibits nitric oxide (NO) production release of RAW 264.7 cells stimulated by Lipopolysaccharide (LPS)[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> NO Synthase

Research Areas >> Inflammation/Immunology

[References]

[1]. Qin Liu, et al. Three new cassane diterpenes from the seeds of Caesalpinia minax Hance. Nat Prod Res. 2018 Apr;32(8):885-891.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
487.0±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₄H₃₄O₆

[ Molecular Weight ]:
418.52

[ Flash Point ]:
248.3±28.7 °C

[ Exact Mass ]:
418.235535

[ PSA ]:
85.97000

[ LogP ]:
4.90

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.547

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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