ALK5-IN-31

Names

[ CAS No. ]:
2785430-87-5

[ Name ]:
ALK5-IN-31

Biological Activity

[Description]:

ALK5-IN-31 (compound Ex-08) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-β-induced SMAD signaling. ALK5-IN-31 has the potential to inhibit growth of tumour in vivo. ALK5-IN-31 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

ALK-5[1].


[References]

[1]. Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent WO2022126133A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H23FN8

[ Molecular Weight ]:
430.48

Related Compounds