Thalidomide-NH-PEG1-NH2 diTFA

Names

[ CAS No. ]:
2768514-19-6

[ Name ]:
Thalidomide-NH-PEG1-NH2 diTFA

Biological Activity

[Description]:

Thalidomide-NH-PEG1-NH2 diTFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[References]

[1]. Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine. Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11.  

[2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.  

Chemical & Physical Properties

[ Molecular Formula ]:
C21H22F6N4O9

[ Molecular Weight ]:
588.41

Related Compounds

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