FAK-IN-14

Names

[ Name ]:
FAK-IN-14

Biological Activity

[Description]:

FAK-IN-14 (compound 8d) is a focal adhesion kinase(FAK) inhibitor with an IC50 value of 0.2438 nM. FAK-IN-14 induces U87-MG cell early apoptosis and arrest the cell at the G2/M phase[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FAK

[References]

[1]. Zhiwu Long, et al. Design, synthesis and biological evaluation of 4-arylamino-pyrimidine derivatives as focal adhesion kinase inhibitors. Bioorg Chem. 2023.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₄BrN₇OS

[ Molecular Weight ]:
502.43

Related Compounds

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