HPK1-IN-37

Names

[ Name ]:
HPK1-IN-37

Biological Activity

[Description]:

HPK1-IN-37 (compound A85) is an inhibitor of HPK1 (IC50=3.7 nM). HPK1-IN-37 can be used for research in HPK1 related disorders or diseases including cancers[1].

[Related Catalog]:

Signaling Pathways >> MAPK/ERK Pathway >> MAP4K

Research Areas >> Cancer

[Target]

IC50: 3.7 nM (MAP4K1/HPK1)[1]

[References]

[1]. Xu S, et al. Preparation of 3-[(1H-pyrazol-4-yl)oxy]pyrazin-2-amine compounds as HPK1 inhibitor and application. World Intellectual Property Organization, WO2022068848 A1. 2022-04-07.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₃₅N₇O₄

[ Molecular Weight ]:
521.61

Related Compounds

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