RAS-IN-2

Names

[ CAS No. ]:
2765081-21-6

[ Name ]:
RAS-IN-2

Biological Activity

[Description]:

RAS-IN-2 (Compound A122) is a potent RAS(ON)MULTI inhibitor and can be used for the research of cancer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

KRas G12D

[In Vitro]

RAS-IN-2 (Compound A122) (5 days) 抑制 AsPC-1 (K-Ras G12D) 的细胞活力，IC50 为 1-10 μM[1]。

[References]

[1]. Ethan AHLER, et al. Use of sos1 inhibitors to treat malignancies with shp2 mutations. Patent WO2022060583A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₄H₅₈N₈O₅S

[ Molecular Weight ]:
811.05

Related Compounds

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