M24

Names

[ CAS No. ]:
2761947-05-9

[ Name ]:
M24

Biological Activity

[Description]:

M24 is a Mcl-1 selective inhibitor. M24 exhibits good binding affinity against Mcl-1 with Ki value of 0.33 μM. M24 exhibits good anti-proliferative activity and induce apoptosis in HepG2 cells[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Bcl-2 Family

Research Areas >> Cancer

[References]

[1]. Xiao Liang, et al. Design, synthesis and biological evaluation of hydantoin derivatives as Mcl-1 selective inhibitors. Bioorg Chem. 2022 Apr;121:105643.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₄H₄₀Cl₃N₅O₁₁S

[ Molecular Weight ]:
953.24

Related Compounds

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