TNG-462

Names

[ Name ]:
TNG-462

Biological Activity

[Description]:

TNG-462 (Compound 1143) is an orally active PRMT5 inhibitor for investigation of MTAP-deficient and/or MTA-accumulating cancers[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Epigenetics >> Histone Methyltransferase

[Target]

PRMT5[1].

[References]

[1]. Kevin M Cottrell, et al. Piperidin-1- yl-n-pyrydi ne-3-yl-2-oxoacet am ide derivatives useful for the treatment of mtap-deficient and/or mt a-accumulating cancers. Patent WO2022026892A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₃₆N₆O₂S

[ Molecular Weight ]:
520.69

Related Compounds

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