TNIK-IN-2

Names

[ CAS No. ]:
2754265-76-2

[ Name ]:
TNIK-IN-2

Biological Activity

[Description]:

TNIK-IN-2 is a Traf2- and Nck-interacting protein kinase (TNIK) inhibitor, with an IC50 of 1.3337 μM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

IC50: 1.3337 μM (TNIK)[1]

[In Vitro]

TNIK-IN-2 (compound 1) inhibits TNIK, with an IC50 of 31.26 μM in HCT116 cells[1].

[References]

[1]. Li Y, et, al. Discovery of 3,4-Dihydrobenzo[ f][1,4]oxazepin-5(2 H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects. J Med Chem. 2022 Jan 5.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₁₉N₃O₃

[ Molecular Weight ]:
373.40

Related Compounds

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