18bioder

Names

[ Name ]:
18bioder

Biological Activity

[Description]:

18BIOder is a neuroprotective inhibitor of GSK-3β, highly selectively inhibiting HIV-1. It is the second generation derivative of 6BIO.

[References]

1. Guendel I, Iordanskiy S, Van Duyne R, Kehn-Hall K, Saifuddin M, Das R, Jaworski E, Sampey GC, Senina S, Shultz L, Narayanan A, Chen H, Lepene B, Zeng C, Kashanchi F. Novel neuroprotective GSK-3β inhibitor restricts Tat-mediated HIV-1 replication. J Virol. 2014 Jan;88(2):1189-208. doi: 10.1128/JVI.01940-13. Epub 2013 Nov 13. PubMed PMID: 24227837; PubMed Central PMCID: PMC3911635.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₇ClN₂O₂

[ Molecular Weight ]:
210.62

Related Compounds

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