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SOS1-IN-6

Names

[ CAS No. ]:
2751718-88-2

[ Name ]:
SOS1-IN-6

Biological Activity

[Description]:

SOS1-IN-6 (compound 33-P1) is a potent SOS1 inhibitor with IC50s of 14.9 and 73.3 nM for SOS1-G12D and SOS1-G12V, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

SOS1-G12D:14.9 nM (IC50)

SOS1-G12V:73.3 nM (IC50)


[References]

[1]. Fused quinazoline derivative, preparation method therefor and application thereof in medicine. WO2021249475A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H28F3N3O2

[ Molecular Weight ]:
471.51


Related Compounds

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