(16β,22R)-14α,17-Epoxy-13,14,20,22-tetrahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone

Names

[ Name ]:
(16β,22R)-14α,17-Epoxy-13,14,20,22-tetrahydroxy-1,15-dioxo-16,24-cyclo-13,14-secoergosta-2,5,25(27)-triene-18,26-dioic acid 18,20:26,22-dilactone

Biological Activity

[Description]:

Physalin C is a natural product that can be found in physalis angulata. Physalin C shows cytotoxic activities against MCF-7 and HepG2 cells[1].

[Related Catalog]:

Research Areas >> Cancer

[In Vitro]

Physalin C (compound 6) (0-100 µM; 72 h) 显示出对 MCF-7 和 HepG2 细胞的细胞毒活性，IC50 分别为 10.5、24.2 µM[1]。 Cell Cytotoxicity Assay[1] Cell Line: MCF-7,HepG2 cells Concentration: 0-100 µM Incubation Time: 72 h Result: Showed cytotoxic activities with IC50s of 10.5, 24.2 µM for MCF-7,HepG2 cells, respectively.

[References]

[1]. Jia-Jia Fan, et al. A Novel Cytotoxic Physalin from Physalis angulata. Natural Product Communications, 2017, 12(10):1589-1591.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₃₀O₉

[ Molecular Weight ]:
510.53200

[ Exact Mass ]:
510.18900

[ PSA ]:
136.43000

[ LogP ]:
1.45910

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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