CHK-336

Names

[ Name ]:
CHK-336

Biological Activity

[Description]:

CHK-336 (Example 1) is an orally active LDHA inhibitor (IC50<1 nM) that inhibits lactate production in mouse hepatocytes. CHK-336 can be used in the study of hyperoxaluria[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Lactate Dehydrogenase

Research Areas >> Metabolic Disease

[References]

[1]. David Andrew Powell, et al. Substituted pyrazolyl compounds and methods of use thereof. Patent WO2021234547A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₀F₂N₄O₄S₂

[ Molecular Weight ]:
530.57

Related Compounds

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