Antiviral agent 43

Names

[ Name ]:
Antiviral agent 43

Biological Activity

[Description]:

Antiviral agent 43 (compound 16) is a potent and orally active influenza A viruses entry inhibitor. Antiviral agent 43 inhibits replications of influenza A strains VH04-H5N1 and PR8-H1N1 with EC50s of 240 nM and 72 nM, respectively[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus

Research Areas >> Infection

[References]

[1]. Irina N Gaisina, et al. Optimization of 4-Aminopiperidines as Inhibitors of Influenza A Viral Entry That Are Synergistic with Oseltamivir. J Med Chem. 2020 Mar 26;63(6):3120-3130.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₂₂ClF₃N₂O

[ Molecular Weight ]:
362.82

Related Compounds

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