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KRAS G12C inhibitor 23

Names

[ CAS No. ]:
2735721-00-1

[ Name ]:
KRAS G12C inhibitor 23

Biological Activity

[Description]:

KRAS G12C inhibitor 23 is a KRAS G12C inhibitor. KRAS G12C inhibitor 23 inhibits H358 cells with an IC50 of 491 nM (WO2021218939A1, compound 1)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Ras

[Target]

KRas G12C


[References]

[1]. Fused ring compound and application thereof in medicine. WO2021218939A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C32H32FN5O3

[ Molecular Weight ]:
553.63

Related Compounds