ERK5-IN-6

Names

[ Name ]:
ERK5-IN-6

Biological Activity

[Description]:

ERK5-IN-6 (compound 5J) is an ERK5 kinase inhibitor with anticancer activity. ERK5-IN-6 exhibits good anti-proliferative activity with the IC50 value of 4.56 µg/mL for A549 cells[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> MAPK/ERK Pathway >> ERK

Signaling Pathways >> Stem Cell/Wnt >> ERK

[Target]

ERK

[References]

[1]. Qin Zhang, et al. Design, synthesis and SAR of novel 7-azaindole derivatives as potential Erk5 kinase inhibitor with anticancer activity. Bioorg Med Chem. 2023 Oct 14:95:117503.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₁N₃

[ Molecular Weight ]:
339.43

[ Storage condition ]:
-20℃

Related Compounds

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